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EGF Receptor Mouse, FITC, Clone: 13, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 612554
Epidermal Growth Factor (EGF) elicits a variety of cellular responses that are initiated by EGF receptor (EGF-R) binding and activation of intrinsic tyrosine kinase activity. Following ligand binding, EGF receptor is autophosphorylated and, in turn, phosphorylates several other endogenous proteins including phospholipase Cγ. These events initiate a number of intracellular responses that include increased levels of intracellular Ca2+ and transient expression of the nuclear oncogene products c-Myc and c-Fos.
Immunofluorescence, Immunoprecipitation, Western Blotting
|Human EGF Receptor aa. 1020-1046|
|Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.|
|Store undiluted at -20°C.|
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