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EGF Receptor Mouse, FITC, Clone: 13, BD

Catalog No. BDB612554 Shop All BD Biosciences Products
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BDB612554 50 μg
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Catalog No. BDB612554 Supplier BD Biosciences Supplier No. 612554

Description

Mouse Monoclonal Antibody

Epidermal Growth Factor (EGF) elicits a variety of cellular responses that are initiated by EGF receptor (EGF-R) binding and activation of intrinsic tyrosine kinase activity. Following ligand binding, EGF receptor is autophosphorylated and, in turn, phosphorylates several other endogenous proteins including phospholipase Cγ. These events initiate a number of intracellular responses that include increased levels of intracellular Ca2+ and transient expression of the nuclear oncogene products c-Myc and c-Fos.

Immunofluorescence, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen EGF Receptor
Applications Immunofluorescence
Classification Monoclonal
Clone 13
Concentration 250μg/mL
Conjugate FITC
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human EGF Receptor aa. 1020-1046
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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