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MilliporeSigma™ anti-EGFR Clone: 528,

Catalog No. GR01L100UG Shop All MilliporeSigma Products
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Quantity:
100 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
GR01L100UG 100 μg Unconjugated
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Catalog No. GR01L100UG Supplier MilliporeSigma™ Supplier No. GR01L100UG
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Description

Mouse Monoclonal Antibody

Specifically detects EGFR Clone: 528 in Human samples, and it is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization

Epidermal growth factor (EGF) initiates its effects on cell growth through interaction with a 170,000 dalton cell surface glycoprotein receptor. Binding of EGF or transforming growth factor a to the receptor activates a tyrosine-specific protein kinase intrinsic to the EGF-receptor protein. The phosphotyrosine content of target cells increases rapidly and the EGF-receptor is phosphorylated on tyrosine residues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EGFR
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization
Classification Monoclonal
Clone 528
Conjugate Unconjugated
Formulation In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Host Species Mouse
Immunogen partially purified, human EGFR from A431 cells
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the ∽170kDa EGF receptor protein in A431 cells and normal skin.
Target Species Human
Content And Storage 2°C to 8°C
Form Purified
Isotype IgG2a
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For Research Use Only

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