MilliporeSigma™ anti-EGFR Clone: EGFR.1,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ GR15L100UG

Catalog No. GR15L100UG

Description

Specifically detects EGFR Clone: EGFR.1 in Human samples, and it is validated for Flow Cytometry, Immunofluorescence, Immunoprecipitation, Neutralization

Epidermal growth factor (EGF) initiates its effects on cell growth through interaction with a 170,000 dalton cell surface glycoprotein receptor. Binding of EGF or transforming growth factor alpha to the receptor activates a tyrosine-specific protein kinase intrinsic to the EGF-receptor protein. The phosphotyrosine content of target cells increases rapidly and the EGF-receptor is phosphorylated on tyrosine residues.

Specifications

• Antigen: EGFR
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry, Immunofluorescence, Immunoprecipitation, Neutralization
• Clone: EGFR.1
• Formulation: In 50mM sodium phosphate, 0.2% gelatin, pH 7.5.
• Immunogen: partially purified, human EGFR from A431 cells
• Regulatory Status: RUO
• Test Specificity: Recognizes the ∽170kDa EGF receptor protein in A431 cells. For neutralization studies Cat. No. GR15L is recommended.
• Content And Storage: 2°C to 8°C
• Isotype: IgG2b

For Research Use Only