ELOVL6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520520
A suggested positive control is human brain tissue lysate. PA5-20520 can be used with blocking peptide PEP-0640.Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
|A 15 amino acid peptide near the amino terminus of the human ELOVL6.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q9H5J4, Q920L5, Q920L6|
|FACE, FAE, LCE; 3-keto acyl-CoA synthase ELOVL6; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast); elongation of very long chain fatty acids protein 6; fatty acid elongase 2; fatty acyl-CoA elongase; hELO2; long-chain fatty-acyl elongase|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|170439, 171402, 79071|
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