EPB41, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human EPB41 peptide using ARM Technology.

Supplier:  Abnova Corporation H00002035K

Catalog No. 89-204-987

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene (MIM 182860), the beta-spectrin gene (MIM 182870), or the band 3 gene (MIM 109270).[supplied by OMIM

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: EPB41
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: EPB41
• Gene Symbols: EPB41
• Immunogen: A synthetic peptide of human EPB41
• Regulatory Status: RUO
• Gene ID (Entrez): 2035
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
• Gene: EPB41
• Gene Alias: 4.1R, EL1, HE
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid