Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ERK (pan ERK) Mouse, Unlabeled, Clone: 16, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610124

 View more versions of this product

Catalog No. BDB610124

Add to cart



The family of serine/threonine kinases known as ERKs (extracellular signal regulated kinases) or MAPKs (mitogen-activated protein kinases) are activated after cell stimulation by a variety of hormones and growth factors. Cell stimulation induces a signaling cascade that leads to phosphorylation of MEK (MAPK/ERK kinase) which, in turn, activates ERK via tyrosine and threonine phosphorylation. A myriad of proteins represent the downstream effectors for the active ERK and implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Activation of ERK is normally transient and cells possess dual specificity phosphatases that are responsible for its down-regulation. Furthermore, multiple studies have shown that elevated ERK activity is associated with some cancers. ERK1 may be observable migrating at 44kDa and ERK2 at 42kDa in addition to a 54kDa ERK and a MAP kinase in the 90kDa range.

Host Species: Mouse
Clone: 16
Isotype: IgG2a
Species Reactivity: Mouse
Immunogen: Rat ERK2 aa. 219-358
Formula Weight [Chemical]: 42-85kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting



ERK (pan ERK)
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Store undiluted at -20°C.
Western Blot
Extracellular signal Regulated Kinases
Affinity Purified
Rat ERK2 aa. 219-358
Cell Biology
Canine, Chicken, Frog, Human, Murine, Rat
Product Certifications


Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only.