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Ezrin (pY353) Mouse anti-Human, Alexa Fluor 488, Clone: I66-386, BD

Catalog No. BDB558627 Shop All BD Biosciences Products
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BDB558627 50 Tests
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Catalog No. BDB558627 Supplier BD Biosciences Supplier No. 558627
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Description

Mouse Monoclonal Antibody

Ezrin is a member of the ERM (ezrin-radixin-moesin) family of proteins that function as crosslinkers between the actin cytoskeleton and the plasma membrane. Ezrin is a substrate for the tyrosine kinase epidermal (EGF) and hepatocyte growth factor (HGF) receptors. Upon EGF or HGF stimulation, ezrin is phosphorylated on tyrosine 353 (Y353), which is required for its interaction with phosphatidylinositol 3 kinase p85 subunit and activation of Akt. The I66-386 monoclonal antibody recognizes the phosphorylated Y353 of human ezrin.

Intracellular Staining

TRUSTED_SUSTAINABILITY

Specifications

Antigen Ezrin (pY353)
Applications Flow Cytometry
Classification Monoclonal
Clone I66-386
Conjugate Alexa Fluor 488
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Phosphorylated Human Ezrin Peptide
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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