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Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Catalog No. 89017629 Shop All Abnova Corporation Products
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100 μg
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89-017-629 100 μg
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Catalog No. 89-017-629 Supplier Abnova Corporation Supplier No. H00002214D01P
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Description

Rabbit polyclonal antibody raised against a full-length human FCGR3A protein.

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: MGGGAGERLFTSSCLVGLVPLGLRISLVTCPLQCGIMWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFFPPGYQVSFCLVMVLLFAVDTGLYFSVKTNIRSSTRDWKDHKFKWRKDPQDK

Specifications

Antigen Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Applications In situ PLA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against a full-length human FCGR3A protein.
Formulation PBS with no preservative; pH 7.4
Gene FCGR3A
Gene Accession No. BC036723.1
Gene Alias CD16/CD16A/FCG3/FCGR3/FCGRIII/FCR-10/FCRIII/FCRIIIA/IGFR3
Gene Symbols FCGR3A
Host Species Rabbit
Immunogen FCGR3A (AAH36723.1, 1 a.a. ∼ 290 a.a) full-length human protein.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2214
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Isotype IgG
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