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FCRL5/FCRL3 (CD307e/c) Mouse anti-Human, Alexa Fluor 647, Clone: 307307, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564343
Description
The 307307 monoclonal antibody specifically binds to Fc receptor-like 5 (FCLR5) and crossreacts with Fc receptor-like 3 (FCLR3). These type I transmembrane glycoproteins have sequences that are homologous to classical Fc γreceptors. FCLR5 is also known as CD307e, FCRH5 (Fc receptor homolog 5) and IRTA2 (immunoglobulin superfamily receptor translocation associated 2) whereas FCLR3 is referred to as CD307c, FCRH3 (Fc Receptor Homolog 3) and IRTA3 (immunoglobulin superfamily receptor translocation associated 3). FCRL5 and FCRL3 are differentially expressed by mature B cell subsets and play key roles in controlling signaling through the B cell receptor.
Specifications
| FCRL5/FCRL3 (CD307e/c) | |
| 307307 | |
| FCRL5/FCRL3; FcRH5/FcRH3; IRTA2/IRTA3 | |
| Affinity Purified | |
| Human FCLR5 Recombinant Protein | |
| The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. | |
| RUO | |
| Primary | |
| Human |
| Flow Cytometry | |
| Alexa Fluor 647 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Murine | |
| IgG2b, κ | |
| 50 Tests | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. | |
| Monoclonal |
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