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FGA, Mouse, Clone: 1D12, Abnova™

Catalog No. 89022078 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-022-078 100 μg
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Catalog No. 89-022-078 Supplier Abnova Corporation Supplier No. H00002243M01
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Description

Mouse monoclonal antibody raised against a full-length recombinant FGA.

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq

Sequence: MFSMSIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSGEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVTANNLLVARVTTEETPHLKARAIKWQMRPEVKPIMKEHIAPREAMLNLALSEVSTLLLWGSLPCPPRLS

Specifications

Antigen FGA
Applications ELISA, Immunoprecipitation, In situ PLA, Western Blot
Classification Monoclonal
Clone 1D12
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a full-length recombinant FGA.
Formulation PBS with no preservative; pH 7.4
Gene FGA
Gene Accession No. BC020764
Gene Alias Fib2/MGC119422/MGC119423/MGC119425
Gene Symbols FGA
Host Species Mouse
Immunogen FGA (AAH20764, 1 a.a. ∼ 218 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2243
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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