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fibrinogen alpha chain, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Catalog No. 89017632 Shop All Abnova Corporation Products
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89-017-632 100 μg
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Catalog No. 89-017-632 Supplier Abnova Corporation Supplier No. H00002243D01P
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Description

Rabbit polyclonal antibody raised against a full-length human FGA protein.

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq

Sequence: MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSGEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVTANNLLVARVTTEETPHLKARAIKWQMRPEVKPIMKEHIAPREAMLNLALSEVSTLLLWGSLPCPPRLS

Specifications

Antigen fibrinogen alpha chain
Applications Immunohistochemistry (PFA fixed), In situ PLA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against a full-length human FGA protein.
Formulation PBS with no preservative; pH 7.4
Gene FGA
Gene Accession No. BC020764
Gene Alias Fib2/MGC119422/MGC119423/MGC119425
Gene Symbols FGA
Host Species Rabbit
Immunogen FGA (AAH20764.1, 1 a.a. ∼ 218 a.a) full-length human protein.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Cell Cycle
Primary or Secondary Primary
Gene ID (Entrez) 2243
Target Species Human, Mouse
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Isotype IgG
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