MilliporeSigma™ anti-FGF8 Clone: 2A10,

Catalog No.	Quantity	Conjugate
ST1630100UG	100 μg	Unconjugated

Catalog No. ST1630100UG Supplier MilliporeSigma™ Supplier No. ST1630100UG

Description

Mouse Monoclonal Antibody

Specifically detects FGF8 Clone: 2A10 in Human, Mouse, Rat samples, and it is validated for ELISA, Immuno Blotting

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.

Specifications

• Antigen: FGF8
• Applications: ELISA, Immunoblot, Immunoblot
• Classification: Monoclonal
• Clone: 2A10
• Conjugate: Unconjugated
• Formulation: In PBS, pH 7.2.
• Host Species: Mouse
• Immunogen: Full-length, recombinant, human FGF8 (aa 65-133), expressed as a GST fusion protein
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the ∽30-35kDa FGF8 protein in PC-12, Jurkat, HepG2, NIH3T3, and Raw 264.7 cells.
• Target Species: Human, Mouse, Rat
• Content And Storage: −20°C
• Form: Purified
• Isotype: IgG2a

For Research Use Only