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  6. Fibronectin Mouse, Unlabeled, Clone: 10, BD

Fibronectin Mouse, Unlabeled, Clone: 10, BD

Catalog No. BDB610077 Shop All BD Biosciences Products
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Description

Mouse Monoclonal Antibody

The 240kDa dimeric fibronectin protein exists in two forms: a soluble protomer in body fluids and an insoluble multimer in the extracellular matrix. The latter is the primary functional form and creates a substrate for cell migration, a role which makes fibronectin vital to embryogenesis and wound response. Fibronectin mediates cytoskeletal organization, cell attachment, and cellular signaling through interactions with cellular receptors. Although various isoforms of fibronectin are derived by alternative splicing, they share a common N-terminus which is a critical region for cell surface binding in an initial step of multimer assembly. Further polymerization steps are regulated by fibronectin/integrin interactions and result in generation of the complex fibrils that constitute the fibronectin matrix.

Host Species: Mouse
Clone: 10
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Fibronectin
Formula Weight [Chemical]: 240kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Fibronectin
Applications Flow Cytometry
Classification Monoclonal
Clone 10
Concentration 250μg/mL
Conjugate Unconjugated
Description FN; LETS
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Fibronectin
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Bovine, Canine, Chicken, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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