Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

FPR1 Rabbit anti-Human, Mouse, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141398

Catalog No. 01-675-527


Add to cart

Description

Description

Principal Names: Formyl Peptide receptor 1 (FPR1); fMet-Leu-Phe receptor (fMLP receptor); N-formylpeptide chemoattractant receptor; FMLP; Official Gene Symbol: FPR1 Gen Bank Accession Number: NP_002020 Gene ID: 2357 (Human) Gene Map Locus: 19q13.4 (Human)  FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeletion, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.

Suggested positive control: human liver protein, liver lysate.
Specifications

Specifications

FPR1
Polyclonal
Unconjugated
PBS with 0.05% sodium azide
P21462, P33766
FPR1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
14293, 2357
Western Blot
1.0 mg/mL
1-3ug/mL
FPR1
Liquid
FPR1
Synthetic peptide corresponding to residues 176-190 of human FPR1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit