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Gαt Mouse, Unlabeled, Clone: 3, BD

Catalog No. BDB610589 Shop All BD Biosciences Products
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Catalog No. Quantity
BDB610589 150 μg
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Catalog No. BDB610589 Supplier BD Biosciences Supplier No. 610589

Description

Mouse Monoclonal Antibody

The GTP binding regulatory proteins (G proteins) consist of three subunits: α, β, and γ. These heterotrimeric proteins function at membranes to relay signals from cell surface receptors to intracellular effectors. The α subunit is unique for each G protein and contains the site of GTP binding and hydrolysis, as well as sites for receptor and effector interactions. The βγ subunit complex interacts directly with receptors and the α subunit. The Gα protein transducin (Gαt) contains 350 amino acids and has been extensively studied as a model for G protein function. Gαt requires GTP in order to bind to its effectors. In the process of effector-Gαt binding, GTP is hydrolyzed and the βγ subunits are displaced. The free Gαt-GDP then reassociates with the βγ subunits and re-loads GTP to repeat the cycle.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Gαt
Applications Western Blot
Classification Monoclonal
Clone 3
Concentration 250μg/mL
Conjugate Unconjugated
Description Gα protein transducin
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Bovine Gαt aa. 282-300
Purification Method Affinity Purified
Quantity 150 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Chicken, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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