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Description
GATA3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This ∽50-kDa nuclear protein regulates the development and subsequent maintenance of multiple tissues. GATA3 is involved in the development of T lymphocytes (regulates T cell receptor subunit gene expression) and the differentiation of mature T cells to become Th2 cells. The expressed levels of normal or mutant GATA3 are also associated with the behaviors of various cancer cells including estrogen receptor-positive breast carcinoma cells.
The L50-823 monoclonal antibody recognizes human and mouse GATA3.
Specifications
Specifications
| Antigen | GATA3 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | L50-823 |
| Conjugate | PE-CF594 |
| Description | Gata-3; GATA binding protein 3; GATA-binding factor 3; HDR |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Conserved peptide between the trans-activation and DNA-binding domains of human, mouse and rat GATA3 |
| Purification Method | Affinity Purified |
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