GATA3 Mouse, Brilliant Violet 421, Clone: L50-823, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 563349

Catalog No. BDB563349

Description

GATA3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This ∽50-kDa nuclear protein regulates the development and subsequent maintenance of multiple tissues. GATA3 is involved in the development of T lymphocytes (regulates T cell receptor subunit gene expression) and the differentiation of mature T cells to become Th2 cells. The expressed levels of normal or mutant GATA3 are also associated with the behaviors of various cancer cells including estrogen receptor-positive breast carcinoma cells.

The L50-823 monoclonal antibody recognizes human and mouse GATA3.

Specifications

• Antigen: GATA3
• Classification: Monoclonal
• Conjugate: Brilliant Violet 421
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Conserved peptide between trans-activation and DNA-binding domains of human, mouse and rat GATA3
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: L50-823
• Description: Gata-3; GATA binding protein 3; GATA-binding factor 3; HDR
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human, Mouse
• Isotype: IgG1 κ