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Description
GATA3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This ∽50kDa nuclear protein regulates the development and subsequent maintenance of multiple tissues. GATA3 is involved in the development of T lymphocytes (regulates T cell receptor subunit gene expression) and the differentiation of mature T cells to become Th2 cells. The expressed levels of normal or mutant GATA3 are also associated with the behaviors of various cancer cells including estrogen receptor-positive breast carcinoma cells. The L50-823 monoclonal antibody recognizes human and mouse GATA3.
Host Species: Mouse
Clone: L50-823
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Conserved peptide between the trans-activation and DNA-binding domains of human, mouse and rat GATA3
Intracellular Staining
Specifications
Specifications
| Antigen | GATA3 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | L50-823 |
| Conjugate | PE-Cyanine7 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Conserved peptide between the trans-activation and DNA-binding domains of human, mouse and rat GATA3 |
| Purification Method | Affinity Purified |
| Quantity | 50 Tests |
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