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GATA4 Mouse, Alexa Fluor 488, Clone: L97-56, BD

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BDB560330 50 Tests
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Catalog No. BDB560330 Supplier BD Biosciences Supplier No. 560330
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Description

Mouse Monoclonal Antibody

The L97-56 monoclonal antibody reacts with GATA4 (GATA-binding protein 4), a member of the GATA family of zinc finger-containing transcription factors that bind to the GATA nucleotide sequence. This ∽50kDa nuclear protein is expressed in mesodermal and definitive endodermal tissues such as the gastrointestinal tract, gonads, and heart. Genetic studies suggest that GATA4 regulates embryonic cardiac development: in mice, disruption of the GATA4 gene leads to defects in heart tube formation, while mutations of GATA4 are associated with atrial septal defects in humans. In the adult heart, GATA4 regulates differentiated gene expression. The roles of GATA4 in endocrine and reproductive functions were recently reviewed.

Host Species: Mouse
Clone: L97-56
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Human GATA4 Peptide

Bioimaging, Intracellular Staining

TRUSTED_SUSTAINABILITY

Specifications

Antigen GATA4
Applications Flow Cytometry
Classification Monoclonal
Clone L97-56
Conjugate Alexa Fluor 488
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human GATA4 Peptide
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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