anti-GCK, MaxPab™ Polyclonal, Abnova

Rabbit Polyclonal

Manufacturer: Abnova Corporation H00002645D01P

 View all options for this product

Catalog No. 89-017-673

  Check Availability
Add to Cart


    Antigen glucokinase (hexokinase 4)
    Conjugate Unlabeled
    Cross Reactivity Human
    Format Affinity Purified
    Host Species Rabbit
    Immunogen GCK (AAH01890.1, 1 a.a. ∽465 a.a) full-length human protein.
    Purification Method Protein A column
    Quantity 100μg
    Regulatory Status RUO
    Research Discipline Kinases
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal

    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

    Host Species: Rabbit
    Species Reactivity [for Features Main]: Human
    Immunogen: GCK (AAH01890.1, 1 a.a. ~ 465 a.a) full-length human protein.

    Detection Antibody, Western Blotting

  • Description & Specifications

Related Products

Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit