Invitrogen™ GDNF Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA124827

Catalog No. PIPA124827

Description

Neutralization: The ND50 is 2.6 μg/mL. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Specifications

• Antigen: GDNF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GDNF
• Gene Alias: AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
• Host Species: Goat
• Purification Method: IgG fraction
• Regulatory Status: RUO
• Gene ID (Entrez): 2668
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Inhibition Assays, Neutralization
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P39905
• Gene Symbols: GDNF
• Immunogen: Recombinant, full length human GDNF protein expressed in E. coli.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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