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GDNF Goat anti-Human, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA124827

Catalog No. PIPA124827


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Description

Description

PA1-24827 detects GDNF from human samples. PA1-24827 has been successfully used in neutralization, inhibition assays, and Western blot procedures. Neutralization: The ND50 is 2.6 µg/mL. The PA1-24827 immunogen is recombit, full length human GDNF protein expressed in E. coli. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson ft.s disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
Specifications

Specifications

GDNF
Polyclonal
Unconjugated
GDNF
Liquid
GDNF
Recombit, full length human GDNF protein expressed in E. coli.
Protein G
RUO
Antibody
Polyclonal
Human
ELISA, Inhibition Assays, Neutralization, Western Blot
1 mg/mL
PBS with no preservative
P39905
Glial cell line-derived neurotrophic factor, Astrocyte-derived trophic factor 1, ATF1, ATF2, HFB1-GDNF
Goat
IgG
200 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2668
Documents
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