Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Gemin 3 Mouse anti-Human, Clone: 12H12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA15779

Catalog No. 01-674-893


Add to cart

Description

Description

MA1-5779 detects Gemin3 in human samples. MA1-5779 has been successfully used in Western blot, immunoprecipitation, immunofluorescence and ELISA procedures. MA1-5779 detects a band of approximately 105 kDa. The MA1-5779 immunogen is recombit 6His-tag COOH-terminal domain of Gemin3.

Gemin 3 is a member of the DEAD box protein family which are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. DEAD box proteins such as Gemin 3 are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of DEAD box family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Gemin 3 has an ATPase activity and a component of the survival of motor neurons (SMN) complex. The Gemin 3 protein may play a catalytic role in the function of the SMN complex on RNPs. Diseases associated with Gemin 3 protein dysfunction include spinal muscular dystrophy and muscular atrophy.
Specifications

Specifications

Gemin 3
Monoclonal
1 mg/mL
PBS with 0.1% sodium azide
Q9UHI6
DKFZp434H052, DP103, GEMIN3
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
11218
ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
12H12
Unconjugated
DDX20
Liquid
DDX20
Recombit 6His-tag COOH-terminal domain of Gemin3 (amino acids 368-548) from SP2/0 cellsal domain of Gemin3.
Protein A
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit