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GFRA1, Mouse, Clone: 4D8, Abnova™

Catalog No. 89022302 Shop All Abnova Corporation Products
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100 μg
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89-022-302 100 μg
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Catalog No. 89-022-302 Supplier Abnova Corporation Supplier No. H00002674M05
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Description

Mouse monoclonal antibody raised against a full-length recombinant GFRA1.

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq

Sequence: ASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDS

Specifications

Antigen GFRA1
Applications ELISA, Immunofluorescence
Classification Monoclonal
Clone 4D8
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a full length recombinant GFRA1.
Formulation PBS with no preservative; pH 7.4
Gene GFRA1
Gene Accession No. NM_005264
Gene Alias GDNFR/GDNFRA/GFR-ALPHA-1/MGC23045/RET1L/RETL1/TRNR1
Gene Symbols GFRA1
Host Species Mouse
Immunogen GFRA1 (NP_005255, 32 a.a. ∼ 119 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2674
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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