GJB2, Mouse, Clone: 1C6, Abnova™

Catalog No.	Quantity
89-022-312	100 μg

Catalog No. 89-022-312 Supplier Abnova Corporation Supplier No. H00002706M01

Description

Mouse monoclonal antibody raised against a full-length recombinant GJB2.

This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq

Sequence: MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEEIKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKKPV

Specifications

• Antigen: GJB2
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 1C6
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full-length recombinant GJB2.
• Formulation: PBS with no preservative; pH 7.4
• Gene: GJB2
• Gene Accession No.: BC017048
• Gene Alias: CX26/DFNA3/DFNB1/HID/KID/NSRD1/PPK
• Gene Symbols: GJB2
• Host Species: Mouse
• Immunogen: GJB2 (AAH17048, 1 a.a. ∼ 226 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2706
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b κ