Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

GM130 Mouse, Unlabeled, Clone: 35/GM130, BD

Mouse Monoclonal Antibody

$281.50 - $558.50

Specifications

Antigen GM130
Clone 35/GM130
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610822
View Documents
BD Biosciences
610822
50 μg
Each for $281.50
Only null left
Add to Cart
 
BDB610823
View Documents
BD Biosciences
610823
150 μg
Each for $558.50
Only null left
Add to Cart
 
Description

Description

Maturation and post-translational modification of proteins occurs after their biosynthesis at the endoplasmic reticulum and their transport through the Golgi apparatus. The process involves the transport of vesicles carrying the proteins through a vectorial process of vesicle budding and fusion from the cis-compartment to the medial-compartment and the trans-compartment of the Golgi apparatus. The detergent insoluble fraction of the Golgi is named “matrix” and is required for proper morphology of the Golgi membranes. GM130 (Golgi matrix protein of 130kDa) is a protein isolated from the Triton™ X-100-insoluble Golgi matrix and peripherally associated with the cis compartment, as demonstrated by co-localization with syntaxin5. GM130 is homologous to the Golgi autoantigen golgin 95. GM130 interacts through its N-terminal domain with p115 and with the Golgi membranes at the C-terminal portion. Furthermore, the mitotic phosphorylation of GM130 blocks the interaction with p115. Thus, GM130 appears to function as a structural element of the Golgi apparatus that also provides attachment sites for membranes and other Golgi proteins. The 35/GM130 monoclonal antibody recognizes GM130, regardless of phosphorylation status.

Host Species: Mouse
Clone: 35
Isotype: IgG1
Species Reactivity [for Features Main]: Human
Immunogen: Rat GM130 aa. 869-982

Immunofluorescence, Immunoprecipitation

Specifications

Specifications

GM130
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1 κ
Affinity Purified
35/GM130
Western Blot
Unconjugated
RUO
Canine, Human, Mouse, Rat
Rat GM130 aa. 869-982
Primary
Store undiluted at -20°C.
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.