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Description
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. [provided by RefSeq
Specifications
Specifications
| Antigen | GM2A |
| Applications | ELISA |
| Classification | Monoclonal |
| Clone | 2C8 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant GM2A. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | GM2A |
| Gene Accession No. | NM_000405 |
| Gene Alias | SAP-3 |
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