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gp49 Receptor Hamster anti-Mouse, Unlabeled, Clone: H1.1, BD

Catalog No. BDB552420 Shop All BD Biosciences Products
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BDB552420 0.1 mg
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Catalog No. BDB552420 Supplier BD Biosciences Supplier No. 552420

Hamster Monoclonal Antibody

The H1.1 antibody reacts with gp49B, a structural homolog of the human Killer Inhibitory Receptors (KIR), and with the truncated related molecule gp49A. The gp49 receptors are expressed on myeloid cells of adult bone marrow, spleen, and liver and fetal liver. They are not found on resting lymphoid cells, but their expression is upregulated on activated NK cells. gp49B is a member of the Ig superfamily containing two cytoplasmic ITIM (Immunoreceptor Tyrosine-based Inhibitory Motif) domains, while gp49A has no ITIM. Although its ligand is unknown, it is established that cross-linking of gp49B can suppress cell activation events.

Host Species: Hamster
Clone: H1.1
Isotype: IgG3 κ
Species Reactivity: Mouse
Immunogen: gp49B-Fc fusion protein composed of extracelluar domain of gp49B

ELISA, Flow Cytometry, Immunoprecipitation

TRUSTED_SUSTAINABILITY

Specifications

Antigen gp49 Receptor
Applications Flow Cytometry
Classification Monoclonal
Clone H1.1
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Hamster
Immunogen gp49B-Fc fusion protein composed of extracelluar domain of gp49B
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG κ3
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For Research Use Only.

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