Invitrogen™ GPD1 Monoclonal Antibody (3C10-1C4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA518997

Catalog No. PIMA518997

Description

Peptide Sequence: MASKKVCIVG SGNWGSAIAK IVGGNAAQLA QFDPRVTMWV FEEDIGGKKL TEIINTQHEN VKYLPGHKLP PNVVAVPDVV QAAEDADILI FVVPHQFIGK ICDQLKGHLK ANATGISLIK GVDEGPNGLK LISEVIGERL GIPMSVLMGA NIASEVADEK FCETTIGCKD PAQGQLLKEL MQTPNFRITV VQEVDTVEIC GTLKNVVAVG AGFCDGLGFG DNTKAAVIRL GLMEMIAFAK LFCSGPVSSA TFLESCGVAD LITTCYGGRN RKVAEAFART GKSIEQLEKE LLNGQKLQGP ETARELYSIL QHKGLVDKFP LFMAVYKVCY EGQPVGEFIH CLQNHPEHM.

This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: GPD1
• Classification: Monoclonal
• Concentration: 0.4 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P21695
• Gene Symbols: Gpd1
• Immunogen: GPD1 (AAH32234, 1 a.a. ~ 349 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Western Blot
• Clone: 3C10-1C4
• Conjugate: Unconjugated
• Gene: Gpd1
• Gene Alias: AI747587; Gdc1; Gdc-1; glycerol 3-phosphate dehydrogenase; glycerol phosphate dehydrogenase 1, cytoplasmic adult; Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; glycerol-3-phosphate dehydrogenase 1; glycerol-3-phosphate dehydrogenase 1 (soluble); glycerolphosphate dehydrogenase 1, cytoplasmic adult; glycerophosphate dehydrogenase; Gpd1; Gpd3; GPD-C; GPDH; GPDH-C; HTGTI; Kiaa4010; mKIAA4010
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2819
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid