GPX4, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human GPX4 peptide using ARM Technology.

Supplier:  Abnova Corporation H00002879K

Catalog No. 89-208-199

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: GPX4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: GPX4
• Gene Symbols: GPX4
• Immunogen: A synthetic peptide of human GPX4
• Regulatory Status: RUO
• Gene ID (Entrez): 2879
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: glutathione peroxidase 4 (phospholipid hydroperoxidase)
• Gene: GPX4
• Gene Alias: MCSP, PHGPx, snGPx, snPHGPx
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid