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growth factor receptor-bound protein 2, Mouse, Clone: 4C6-H6, Abnova™

Catalog No. 89001458 Shop All Abnova Corporation Products
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200 μL
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89-001-458 200 μL
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Catalog No. 89-001-458 Supplier Abnova Corporation Supplier No. H00002885M01A
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Description

Mouse monoclonal antibody raised against a full-length recombinant GRB2.

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C. elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV

Specifications

Antigen growth factor receptor-bound protein 2
Applications ELISA, Western Blot
Classification Monoclonal
Clone 4C6-H6
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a full length recombinant GRB2.
Formulation ascites with no preservative
Gene GRB2
Gene Accession No. BC000631
Gene Alias ASH/EGFRBP-GRB2/Grb3-3/MST084/MSTP084
Gene Symbols GRB2
Host Species Mouse
Immunogen GRB2 (AAH00631, 1 a.a. ∼ 217 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity 200 μL
Regulatory Status RUO
Research Discipline Signal Transduction
Whole Molecule Yes
Primary or Secondary Primary
Gene ID (Entrez) 2885
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Ascites
Isotype IgM κ
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