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GREM1 (C-terminus), Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of GREM1.

Manufacturer:  Abnova Corporation PAB4716

Catalog No. 89-024-842


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Description

Description

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. [provided by RefSeq

Specifications

Specifications

GREM1 Ab-1
Unconjugated
ELISA (1:1000) Western Blot (1:100-500) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
GREM1
CKTSF1B1|DAND2|DRM|GREMLIN|IHG-2|MGC126660|PIG2
Rabbit
400 uL
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human, Murine
ELISA, Immunohistochemistry, Immunohistochemistry (PFA fixed), Western Blot
Rabbit polyclonal antibody raised against synthetic peptide of GREM1.
In PBS (0.09% sodium azide)
Liquid
GREM1
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GREM1.
RUO
Primary
26585
Documents
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