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GRLF1, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human GRLF1 peptide using ARM Technology.

Supplier:  Abnova Corporation H00002909K

Catalog No. 89-208-201


Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Description

The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Specifications

GRLF1
Monoclonal
Unconjugated
In 1X PBS, pH 7.4
GRLF1
GRLF1
A synthetic peptide of human GRLF1
RUO
2909
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG
ELISA, Western Blot
1mg
glucocorticoid receptor DNA binding factor 1
GRLF1
GRF-1, KIAA1722, MGC10745, P190-A, P190A, p190RhoGAP
Rabbit
1 mg x up to 3 Abs
Primary
Human
Liquid
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