GRLF1, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human GRLF1 peptide using ARM Technology.

Supplier:  Abnova Corporation H00002909K

Catalog No. 89-208-201

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: GRLF1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: GRLF1
• Gene Symbols: GRLF1
• Immunogen: A synthetic peptide of human GRLF1
• Regulatory Status: RUO
• Gene ID (Entrez): 2909
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: glucocorticoid receptor DNA binding factor 1
• Gene: GRLF1
• Gene Alias: GRF-1, KIAA1722, MGC10745, P190-A, P190A, p190RhoGAP
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid