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GST-π Mouse, Unlabeled, Clone: 3, BD

Catalog No. BDB610718 Shop All BD Biosciences Products
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BDB610719 150 μg
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Catalog No. BDB610718 Supplier BD Biosciences Supplier No. 610718
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Description

Mouse Monoclonal Antibody

Glutathione-S-Transferases (GSTs) are a family of dimeric proteins that catalyze the S-conjugation of glutathione with many compounds for detoxification. The GSTs are categorized into four classes based on their biochemical and structural properties: α, μ, π, and θ. GST-π is of particular interest because it is over-expressed in many tumors, but is either absent or expressed at low levels in the corresponding normal tissues. This high expression of GST-π is associated with malignant transformation and correlates with a decrease in GST activity. Three different GST-π proteins have been isolated and designated as hGSTP1™A, hGSTP1™B, and hGSTP1™C. These isoforms are nearly identical, varying by only one to two amino acids.

Immunofluorescence, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen GST-π
Applications Western Blot
Classification Monoclonal
Clone 3
Concentration 250μg/mL
Conjugate Unconjugated
Description Glutathione-S-Transferase-π
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human GST-π aa. 5-210
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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