GSTA4, Rabbit, Monoclonal Antibody, Abnova™
Rabbit monoclonal antibody raised against a human GSTA4 peptide using ARM Technology.
Manufacturer: Abnova Corporation H00002941K
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. [provided by RefSeqLibrary Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
|glutathione S-transferase alpha 4|
|A synthetic peptide of human GSTA4|
|1mg x up to 3 Abs|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|ELISA, Western Blot|
|In 1X PBS, pH 7.4|
|DKFZp686D21185, GSTA4-4, GTA4|
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