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Description
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq
Specifications
Specifications
| Antigen | GTF3A |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 4B4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant GTF3A. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | GTF3A |
| Gene Accession No. | NM_002097 |
| Gene Alias | AP2/TFIIIA |
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