GTPBP4, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human GTPBP4 peptide using ARM Technology.

Supplier:  Abnova Corporation H00023560K

Catalog No. 89-204-449

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq]

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: GTPBP4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: GTPBP4
• Gene Symbols: GTPBP4
• Immunogen: A synthetic peptide of human GTPBP4
• Regulatory Status: RUO
• Gene ID (Entrez): 23560
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: GTP binding protein 4
• Gene: GTPBP4
• Gene Alias: CRFG, FLJ10686, FLJ10690, FLJ39774, NGB, NOG1
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid