GZMB, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human GZMB peptide using ARM Technology.

Supplier:  Abnova Corporation H00003002K

Catalog No. 89-206-040

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq]

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: GZMB
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: GZMB
• Gene Symbols: GZMB
• Immunogen: A synthetic peptide of human GZMB
• Regulatory Status: RUO
• Gene ID (Entrez): 3002
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
• Gene: GZMB
• Gene Alias: CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid