H-2D[b] Mouse anti-Mouse, Biotin, Clone: 28-14-8, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 553601

Catalog No. BDB553601

Description

The 28-14-8 antibody reacts with the α3 domain of the H-2D[b] MHC class I alloantigen. The antibody binds to H-2D[b] in the presence or absence of the β2 microglobulin chain. It cross reacts with the α3 domain of H-2L[d], but not with K[d] or D[d], and with H-2D[q] and/or L[q]. Reactivity with haplotypes k, f, p, r, and s has not been observed. mAb 28-14-8 has been shown to block H-2L[d]- specific and H-2L[d]-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes (CTL), but it does not block recognition of H-2L[d] positive target cells by Ly-6G2-positive NK cells.

Host Species: Mouse
Clone: 28-14-8
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: C3H.SW mouse splenocytes

Flow Cytometry, Immunohistochemistry (Frozen)

Specifications

• Antigen: H-2D[b]
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: C3H.SW mouse splenocytes
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2a κ

• Applications: Flow Cytometry
• Clone: 28-14-8
• Conjugate: Biotin
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.