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H-2D[b] Mouse anti-Mouse, Biotin, Clone: 28-14-8, BD

Catalog No. BDB553601 Shop All BD Biosciences Products
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BDB553601 0.5 mg
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Catalog No. BDB553601 Supplier BD Biosciences Supplier No. 553601

Description

Mouse Monoclonal Antibody

The 28-14-8 antibody reacts with the α3 domain of the H-2D[b] MHC class I alloantigen. The antibody binds to H-2D[b] in the presence or absence of the β2 microglobulin chain. It cross reacts with the α3 domain of H-2L[d], but not with K[d] or D[d], and with H-2D[q] and/or L[q]. Reactivity with haplotypes k, f, p, r, and s has not been observed. mAb 28-14-8 has been shown to block H-2L[d]- specific and H-2L[d]-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes (CTL), but it does not block recognition of H-2L[d] positive target cells by Ly-6G2-positive NK cells.

Host Species: Mouse
Clone: 28-14-8
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: C3H.SW mouse splenocytes

Flow Cytometry, Immunohistochemistry (Frozen)

TRUSTED_SUSTAINABILITY

Specifications

Antigen H-2D[b]
Applications Flow Cytometry
Classification Monoclonal
Clone 28-14-8
Concentration 0.5mg/mL
Conjugate Biotin
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen C3H.SW mouse splenocytes
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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