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H-2D(d) Mouse anti-Mouse, Unlabeled, Clone: 34-5-8S, BD

Catalog No. BDB558915 Shop All BD Biosciences Products
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BDB558915 0.1 mg
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Catalog No. BDB558915 Supplier BD Biosciences Supplier No. 558915

Description

Mouse Monoclonal Antibody

The 34-5-8S antibody recognizes an epitope on the N-terminal domains, α1 and α2, of the H-2Dd. The mAb identifies a conformationally sensitive epitope of H-2Dd associated with β2 microglobulin; it fails to react with free H-2D(d) α chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with other haplotypes (e.g., f, k, p, r) has not been observed. mAb 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, C+, F+, G2+, or I+ NK cells or transfectants. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Flow Cytometry, Immunoprecipitation

TRUSTED_SUSTAINABILITY

Specifications

Antigen H-2D(d)
Applications Flow Cytometry
Classification Monoclonal
Clone 34-5-8S
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen (C57BL/6 x DBA/2)F1 hybrid mouse splenocytes
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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