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Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq
Specifications
Specifications
| Antigen | HDAC6 |
| Applications | ELISA, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | 3A6 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a full-length recombinant HDAC6. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | HDAC6 |
| Gene Accession No. | BC013737 |
| Gene Alias | FLJ16239/HD6/JM21 |
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