HDAC6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA131473

Catalog No. PIPA131473

Description

PA1-31473 detects HDAC6 from rat, mouse, human samples. PA1-31473 has been successfully used in Chimmunoprecipitation, immunohistochemistry (paraffin tissue), Western blot applications. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Specifications

• Antigen: HDAC6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q9UBN7, Q9Z2V5
• Gene Symbols: HDAC6
• Immunogen: Proprietary immunogen
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Gene: HDAC6
• Gene Alias: FLJ16239, HD6, JM21
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10013, 15185, 84581
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid