HEC1 Goat anti-Human, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA126543

Catalog No. PIPA126543

Description

PA1-26543 detects HEC1 from human samples. PA1-26543 has been successfully used in Western blot procedures. The PA1-26543 immunogen is a synthetic peptide corresponding to residues Y E K K A T L I K S S E E of HEC1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.

Specifications

• Antigen: HEC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDC80
• Format: Liquid
• Gene Symbols: NDC80
• Immunogen: Synthetic peptide corresponding to residues Y E K K A T L I K S S E E of HEC1.
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O14777
• Gene Alias: HEC, HEC1, KNTC2, TID3, hsNDC80
• Host Species: Goat
• Isotype: IgG
• Quantity: 100 μg
• Storage Requirements: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Primary or Secondary: Primary
• Gene ID (Entrez): 10403