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Description
Monoclonal antibody BB9 recognizes a cell-surface glycoprotein of approximately 160kDa, expressed on primitive hematopoietic progenitor cells (HPC). This antibody was generated using human bone marrow-derived stromal cells as immunogen. BB9 reacts with stromal cells, a minor subset of human bone marrow cells; it does not react with peripheral blood leukocytes. Reacts with a subset of CD34+, CD90+ demonstrating low or absent expression of CD38, low retention of Rhodamine 123 and Ki-67-. CD34+BB9+ cells are able to sustainm hematopoiesis in pre-CFU culture stimulated with IL-3, IL-6, G-CSF and SCF. BB9 also reacts with a subset of CD34+ cells from mobilized peripheral blood.
Host Species: Mouse
Clone: BB9
Isotype: IgG1, κ
Cross Reactivity: Human
Flow Cytometry
Specifications
Specifications
| Antigen | Hematopoietic progenitor cell |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | BB9 |
| Conjugate | PE |
| Description | ACE1; DCP1; Kininase II |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human bone marrow-derived stromal cells |
| Purification Method | Affinity Purified |
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Safety and Handling
For Research Use Only.
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