HER-2/neu Mouse anti-Human, APC, Clone: NEU 24.7, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 340554

Catalog No. BDB340554

Description

Anti-HER-2/neu recognizes a single protein of 185kDa from HER-2 transfected cells.The HER-2/neu antigen, product of the c-erbB2 gene, is a surface marker on some breast cancer cells. Amplification and/or overexpression of HER-2/neu occurs in multiple human malignancies. Overexpression is reported to be strongly correlated with progression of human ovarian and breast carcinomas. Anti-HER-2/neu stains the external domain of this protein on cells such as the strongly expressing line SKBR3 and the weakly expressing line MCF7.

Applications:

Flow Cytometry

Specifications

• Antigen: HER-2/neu
• Classification: Monoclonal
• Conjugate: APC
• Host Species: Mouse
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: NEU 24.7
• Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
• Immunogen: SKBR3 human breast carcinoma cells
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

For Research Use Only.