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hemochromatosis, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length human HFE protein.
Supplier: Abnova Corporation H00003077B01P
Description
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq
Sequence: MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERESpecifications
hemochromatosis | |
Polyclonal | |
Mouse polyclonal antibody raised against a full-length human HFE protein. | |
HFE | |
HFE1/HH/HLA-H/MGC103790/dJ221C16.10.1 | |
Mouse | |
Affinity Purified | |
RUO | |
Primary | |
Human | |
Antibody |
Flow Cytometry, Western Blot | |
Unconjugated | |
PBS with no preservative; pH 7.4 | |
NM_000410.3 | |
HFE | |
HFE (NP_000401.1, 1 a.a. ∼ 348 a.a) full-length human protein. | |
50 μg | |
Membrane Receptors | |
3077 | |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
IgG |
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