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hemochromatosis, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Catalog No. 89016811 Shop All Abnova Corporation Products
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89-016-811 50 μg
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Catalog No. 89-016-811 Supplier Abnova Corporation Supplier No. H00003077B01P
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Description

Mouse polyclonal antibody raised against a full-length human HFE protein.

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq

Sequence: MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Specifications

Antigen hemochromatosis
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a full-length human HFE protein.
Formulation PBS with no preservative; pH 7.4
Gene HFE
Gene Accession No. NM_000410.3
Gene Alias HFE1/HH/HLA-H/MGC103790/dJ221C16.10.1
Gene Symbols HFE
Host Species Mouse
Immunogen HFE (NP_000401.1, 1 a.a. ∼ 348 a.a) full-length human protein.
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Membrane Receptors
Primary or Secondary Primary
Gene ID (Entrez) 3077
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Isotype IgG
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