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hemochromatosis, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human HFE protein.

Supplier:  Abnova Corporation H00003077B01P

Catalog No. 89-016-811


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Description

Description

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq

Sequence: MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Specifications

Specifications

hemochromatosis
Polyclonal
Mouse polyclonal antibody raised against a full-length human HFE protein.
HFE
HFE1/HH/HLA-H/MGC103790/dJ221C16.10.1
Mouse
Affinity Purified
RUO
Primary
Human
Antibody
Flow Cytometry, Western Blot
Unconjugated
PBS with no preservative; pH 7.4
NM_000410.3
HFE
HFE (NP_000401.1, 1 a.a. ∼ 348 a.a) full-length human protein.
50 μg
Membrane Receptors
3077
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG
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