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HGF, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human HGF peptide using ARM Technology.

Manufacturer:  Abnova Corporation H00003082K

Catalog No. 89-200-468

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Description

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69kDa alpha-chain and 34kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Specifications

HGF
1mg
hepatocyte growth factor (hepapoietin A; scatter factor)
HGF
Liquid
HGF
A synthetic peptide of human HGF
1mg x up to 3 Abs
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
ELISA, Western Blot
Unconjugated
In 1X PBS, pH 7.4
HGF
F-TCF, HGFB, HPTA, SF
Rabbit
IgG
RUO
Primary
3082
SDS
Documents
Product Certifications
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