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Histone H2B Rabbit anti-Canine, Chicken, Drosophila, Human, Mouse, Rat, Zebrafish, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141058

Catalog No. 01-676-656

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This peptide sequence is 100% conserved between multiple species including human, mouse, rat, dog, chimpanzee, cow, chicken, duck, zebrafish, and drosophila. Suggested positive control: Jurkat, PBMC.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.


Histone H2B
His2B:CG17949, HIST1H2B7, HIST1H2BB, hist2h2l, LOC608682
Synthetic peptide corresponding to amino acids 111-125 of human histone H2B [GenBank no. CAI19747.1]
Protein G
Canine, Chicken, Drosophila, Human, Mouse, Rat, Zebrafish
ChIP assay, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.05% sodium azide
P0C1H3, P02283, P33778, Q64475, Q6PC60
RP1-193B12.10, H2B/d, H2BFD, HIST1H3I, MGC125414, MGC125415, MGC125416, MGC9388
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
326273, 386920, 319178, 417956, 3018, 608682
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