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HLA-DMA, Mouse, Clone: 3F12-F11, Abnova™

Catalog No. 89022495 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-022-495 100 μg
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Catalog No. 89-022-495 Supplier Abnova Corporation Supplier No. H00003108M01
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Description

Mouse monoclonal antibody raised against a full-length recombinant HLA-DMA.

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq

Sequence: MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGD

Specifications

Antigen HLA-DMA
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Monoclonal
Clone 3F12-F11
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a full length recombinant HLA-DMA.
Formulation PBS with no preservative; pH 7.4
Gene HLA-DMA
Gene Accession No. BC011447
Gene Alias D6S222E/DMA/HLADM/RING6
Gene Symbols HLA-DMA
Host Species Mouse
Immunogen HLA-DMA (AAH11447, 1 a.a. ∼ 261 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3108
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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