HLA-DQ Mouse anti-Human, FITC, Clone: SK10, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 347453

Catalog No. BDB347453

Description

The Anti–HLA-DQ antibody, clone SK10, is derived from the hybridization of NS-1 mouse myeloma cells with spleen cells isolated from BALB/c mice immunized with tonsillar B lymphocytes (non–E-rosetting cells).

Anti-HLA-DQ (Leu-10) recognizes a class II major histocompatibility complex (MHC) antigen, Mr 26 to 34 kdaltons (kDa), distinct from HLA-DR and HLA-DP antigens. Anti-HLA-DQ recognizes a common polymorphic epitope present on HLA-DQ molecules of cells expressing DQw1 and DQw3 (usually associated with DR1, DR2, DR4, DR5, DRw8, DRw9, and DRw10) and absent from DQw2 (usually associated with DR3, and DR7). Therefore, Anti-HLA-DQ will not react with cells from DR3 or DR 7 homozygotes or DR3/7 heterozygotes.

Specifications

• Antigen: HLA-DQ
• Classification: Monoclonal
• Concentration: 25μg/mL
• Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: SK10
• Conjugate: FITC
• Host Species: Mouse
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

For Research Use Only.