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HLA-DR Mouse anti-Human, BUV395, Clone: G46-6, BD

Catalog No. BDB564040 Shop All BD Biosciences Products
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Catalog No. BDB564040 Supplier BD Biosciences Supplier No. 564040
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Description

Mouse Monoclonal Antibody

The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen HLA-DR
Applications Flow Cytometry
Classification Monoclonal
Clone G46-6
Conjugate Brilliant Ultraviolet 395
Description MHC class II antigen; HLA class II histocompatibility antigen
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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